MLB · Sat, Apr 25 · 7:10 PM

Pirates at Brewers

O/U 7.5 · RL Brewers -1.5 · American Family Field

Gary's pick

Pirates ML+120

CONF 65%

Result

WCashedFinal 6-3

The read

The roof is closed tonight at American Family Field as the surging Pirates look to clinch their first series in Milwaukee in years, while the Brewers desperately search for an answer to a four-game skid that has seen their offense nearly vanish. After Paul Skenes flirted with perfection yesterday, the Pirates turn to veteran Mitch Keller to keep the momentum rolling against Milwaukee's flamethrower Jacob Misiorowski.

The market has installed the Brewers as favorites here, likely banking on Misiorowski's elite "stuff" and Keller's historically poor record against this organization. But we aren't betting on history; we are betting on what’s happening in April 2026. Misiorowski is a strikeout machine, averaging 14.2 K/9, but he is a high-variance arm who rarely works deep into games. When he exits, he hands the ball to a Brewers bullpen that has been a house of cards lately, with primary arms like Trevor Megill and Angel Zerpa carrying ERAs over 6.00. Contrast that with a Pirates bullpen anchored by Gregory Soto and Dennis Santana, both of whom have been near-automatic and remain fresh after yesterday's light workload.

The real edge here is the massive disparity in offensive confidence. Milwaukee’s lineup is currently a shell of its projected self, having managed just one hit in yesterday’s shutout and totaling only one home run over their last nine games. While Brice Turang remains a spark, the rest of the order is struggling to generate hard contact. The Pirates, meanwhile, have found a new gear with the arrival of Konnor Griffin, who homered in his debut yesterday, and Oneil Cruz, who is currently hitting the ball harder than anyone in the league. Keller doesn't need to be perfect; he just needs to be the efficient innings-eater he has been all season to outlast the Brewers' prospect and get the game to his superior relief corps. At +120, I’m riding the hot hand in Pittsburgh.

Injuries noted

Brewers: [NEW] Andrew Vaughn (First Baseman) — Hand (Left): Vaughn (hand) began hitting on the field Friday, Adam McCalvy of MLB.com reports. (Apr 24 — 1d ago) [KNOWN] Jackson Chourio (Left Fielder) — Hand (Left): Chourio (hand) will hit on the field Wednesday, Adam McCalvy of MLB.com reports. (Apr 21 — 4d ago) [KNOWN] Christian Yelich (Left Fielder) — Groin (Left): Yelich (groin) is expected to be sidelined until mid- to late-May, Curt Hogg of the Milwaukee Journal Sentinel reports. (Apr 14 — 11d ago) [KNOWN] Rob Zastryzny (Relief Pitcher) — Ribs (Left): Zastryzny (shoulder) was diagnosed with an intercostal strain and will be sidelined until at least late April, Todd Rosiak of the Milwaukee Journal Sentinel reports. (Apr 14 — 11d ago) [KNOWN] Jared Koenig (Relief Pitcher) — Elbow (Left): Koenig allowed a hit and struck out one over a scoreless inning to earn the save in Thursday's 5-2 win over the Angels. (Apr 6 — 19d ago) [KNOWN] Akil Baddoo (Left Fielder) — Quadriceps (Left): The Brewers placed Baddoo (quadriceps) on the 60-day injured list Tuesday, Adam McCalvy of MLB.com reports. (Mar 24 — 32d ago) Pirates: [NEW] Braxton Ashcraft (Relief Pitcher) — Personal: The Pirates placed Ashcraft (personal) on the bereavement/family medical emergency list Saturday. (Apr 25 — 0d ago) [NEW] Jared Triolo (Third Baseman) — Knee (Right): Triolo (knee) will begin a rehab assignment with Single-A Bradenton on Friday, Kevin Gorman of TribLive.com reports. (Apr 24 — 1d ago)

About this analysis

Who made it
Gary AI, an AI sports-analysis product operated by Gary A.I. LLC. No human reviewer is claimed unless one is explicitly named.
Published data
Board stored April 25, 2026 at 10:39 AM ET.
Odds record
The displayed line is the value retained with the call. Stored sportsbook sources: fanduel, fanatics, caesars, draftkings, betrivers, betmgm.
Accountability
Read the editorial standards, source policy, and corrections process.

Props on this game

2

Every pick posts before the game and is graded after, in public. In the app you can ride or fade any of them, and your book keeps score against Gary's.

Download on the App Store

Every MLB game this dayThe MLB recordToday's MLB board