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MLB · Sat, Apr 25 · 7:10 PM

Pirates at Brewers

O/U 7.5 · RL Brewers -1.5 · American Family Field

GARY'S PICK
Pirates Moneyline
MLB@ Brewers· +120

Pirates
Moneyline

+120 · CASHED · PIT 6 · MIL 3

Brewers

The pick & result

Published pick
Pirates ML +120
Published odds
+120
Result
Won
Final score
6-3

Odds are the American price printed with this pick, not a current offer. Wins, losses and pushes remain on the public record; a missing grade is not a win.

The read

The roof is closed tonight at American Family Field as the surging Pirates look to clinch their first series in Milwaukee in years, while the Brewers desperately search for an answer to a four-game skid that has seen their offense nearly vanish. After Paul Skenes flirted with perfection yesterday, the Pirates turn to veteran Mitch Keller to keep the momentum rolling against Milwaukee's flamethrower Jacob Misiorowski.

The market has installed the Brewers as favorites here, likely banking on Misiorowski's elite "stuff" and Keller's historically poor record against this organization. But we aren't betting on history; we are betting on what’s happening in April 2026. Misiorowski is a strikeout machine, averaging 14.2 K/9, but he is a high-variance arm who rarely works deep into games. When he exits, he hands the ball to a Brewers bullpen that has been a house of cards lately, with primary arms like Trevor Megill and Angel Zerpa carrying ERAs over 6.00. Contrast that with a Pirates bullpen anchored by Gregory Soto and Dennis Santana, both of whom have been near-automatic and remain fresh after yesterday's light workload.

The real edge here is the massive disparity in offensive confidence. Milwaukee’s lineup is currently a shell of its projected self, having managed just one hit in yesterday’s shutout and totaling only one home run over their last nine games. While Brice Turang remains a spark, the rest of the order is struggling to generate hard contact. The Pirates, meanwhile, have found a new gear with the arrival of Konnor Griffin, who homered in his debut yesterday, and Oneil Cruz, who is currently hitting the ball harder than anyone in the league. Keller doesn't need to be perfect; he just needs to be the efficient innings-eater he has been all season to outlast the Brewers' prospect and get the game to his superior relief corps. At +120, I’m riding the hot hand in Pittsburgh.

Injuries noted

Brewers: [NEW] Andrew Vaughn (First Baseman) — Hand (Left): Vaughn (hand) began hitting on the field Friday, Adam McCalvy of MLB.com reports. (Apr 24 — 1d ago) [KNOWN] Jackson Chourio (Left Fielder) — Hand (Left): Chourio (hand) will hit on the field Wednesday, Adam McCalvy of MLB.com reports. (Apr 21 — 4d ago) [KNOWN] Christian Yelich (Left Fielder) — Groin (Left): Yelich (groin) is expected to be sidelined until mid- to late-May, Curt Hogg of the Milwaukee Journal Sentinel reports. (Apr 14 — 11d ago) [KNOWN] Rob Zastryzny (Relief Pitcher) — Ribs (Left): Zastryzny (shoulder) was diagnosed with an intercostal strain and will be sidelined until at least late April, Todd Rosiak of the Milwaukee Journal Sentinel reports. (Apr 14 — 11d ago) [KNOWN] Jared Koenig (Relief Pitcher) — Elbow (Left): Koenig allowed a hit and struck out one over a scoreless inning to earn the save in Thursday's 5-2 win over the Angels. (Apr 6 — 19d ago) [KNOWN] Akil Baddoo (Left Fielder) — Quadriceps (Left): The Brewers placed Baddoo (quadriceps) on the 60-day injured list Tuesday, Adam McCalvy of MLB.com reports. (Mar 24 — 32d ago) Pirates: [NEW] Braxton Ashcraft (Relief Pitcher) — Personal: The Pirates placed Ashcraft (personal) on the bereavement/family medical emergency list Saturday. (Apr 25 — 0d ago) [NEW] Jared Triolo (Third Baseman) — Knee (Right): Triolo (knee) will begin a rehab assignment with Single-A Bradenton on Friday, Kevin Gorman of TribLive.com reports. (Apr 24 — 1d ago)

About this analysis

Who made it
Gary AI, an AI sports-analysis product operated by Gary A.I. LLC. No human reviewer is claimed unless one is explicitly named.
Published data
Daily picks first stored April 25, 2026 at 10:39 AM ET.
Odds record
The pick receipt shows the price printed in the published ticket. The matchup market and line ladder provide separate market context. Stored sportsbook sources: fanduel, fanatics, caesars, draftkings, betrivers, betmgm.
Accountability
Read the editorial standards, source policy, and corrections process.

Props on this game

2
  • GARY'S PICK
    JACOB MISIOROWSKIK'S OVER 7.5
    MLBBrewers· +110

    Jacob Misiorowski
    K'S over 7.5

    +110 · CASHED · ACTUAL 9

    Brewers

    Jacob Misiorowski has been the most dominant strikeout pitcher in the league through the first month of the 2026 season. His elite velocity (98.8 mph) and high-whiff breaking stuff have translated to a staggering 14.2 K/9.

    He has recorded 7 or more strikeouts in four of his five starts, including three double-digit strikeout performances. He faces a Pittsburgh Pirates lineup that features several high-strikeout profiles, most notably Oneil Cruz (12 K in last 10 games) and Brandon Lowe.

    While Misiorowski struggles with walks, his strikeout efficiency is so high that he only needs to pitch 5.0 innings to have a significant chance at clearing this line. At plus money, the value lies with the over on one of the game's premier young flamethrowers.

  • GARY'S PICK
    WILLIAM CONTRERASTOTAL BASES OVER 1.5
    MLBBrewers· +132

    William Contreras
    Total Bases over 1.5

    +132 · CASHED · ACTUAL 5

    Brewers

    With Christian Yelich, Jackson Chourio, and Andrew Vaughn all sidelined, William Contreras is the undisputed focal point of the Brewers' offense. He has been remarkably consistent, batting .341 over his last 10 games and recording hits in 9 of those 10 contests.

    Tonight's matchup against Mitch Keller is favorable; Keller is a contact-oriented pitcher who currently ranks among the lowest in the league in strikeout rate (5.9 K/9). This translates to more balls in play for Contreras, who possesses elite gap-to-gap power.

    Batting second behind Brice Turang, Contreras should see competitive pitches as the Pirates look to avoid putting two runners on for the middle of the order. Given his high multi-hit frequency (50% in last 10), Contreras is a strong bet to clear two total bases through either multiple hits or an extra-base knock.

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