MLB · Sat, Mar 28 · 2:20 PM

Nationals at Cubs

O/U 8.5 · RL Cubs -1.5 · Wrigley Field

Gary's pick

Chicago Cubs -1.5-118

CONF 85%

Result

WCashedFinal 2-10

The read

Welcome to Wrigley Field, where the biting 42-degree Chicago wind hasn't cooled down the bats just yet, as the 0-1 Cubs look to bounce back in Game 2 against the visiting 1-0 Nationals. Thursday's opener saw Washington jump out to a 10-4 win, but the script flips dramatically this afternoon. The starting pitching discrepancy is arguably the widest on the entire Saturday slate. The Cubs are handing the ball to rising ace Cade Horton, who was practically untouchable here last season with a 1.63 Home ERA and a 1.08 WHIP. He followed that up with 14 strikeouts in his two spring starts. On the other side, the Nationals are rolling out 37-year-old Miles Mikolas, who posted a 4.84 ERA overall last year but a disastrous 6.39 ERA on the road.

If there is a specific pitcher the Cubs lineup wants to see on the mound, it is Mikolas. Chicago's active roster boasts a collective .872 OPS against the veteran right-hander. The individual numbers are staggering: Pete Crow-Armstrong is 7-for-9 with 5 career home runs against him, and Nico Hoerner is 14-for-39 (.359) lifetime. Mikolas has struggled mightily against left-handed hitting, surrendering 17 home runs and a 5.27 ERA to lefties on the road in 2025. With the wind blowing out to right field at 8 mph today, Mikolas's declining 40.2% ground ball rate is a massive liability against left-handed power threats like Michael Busch, who launched 34 homers last season.

Washington capitalized on Chicago's mistakes in Game 1, but they won't get the same free passes today. The Friday off-day completely reset the bullpens, meaning the Cubs have their top high-leverage arms fully available to back up Horton. Furthermore, Chicago's elite defensive infield, which committed 35% fewer errors than Washington in 2025, provides a sturdy floor behind their strikeout pitcher. You don't overreact to one Opening Day blowout in a 162-game season. The Cubs have the superior starter, the perfect historical matchups at the plate, and a prime weather environment to chase Mikolas early. Lay the run line with the home team.

Injuries noted

Cubs: [NEW] Porter Hodge (Relief Pitcher) — Elbow (Right): The Cubs placed Hodge (elbow) on the 15-day injured list Wednesday. (Mar 25 — 2d ago) [NEW] Seiya Suzuki (Right Fielder) — Knee (Right): The Cubs placed Suzuki (knee) on the 10-day injured list Wednesday. (Mar 25 — 3d ago) [KNOWN] Julian Merryweather (Relief Pitcher) — Hamstring (Left): The Twins reassigned Merryweather (hamstring) to minor-league camp Monday. (Mar 22 — 6d ago) Nationals: [KNOWN] Paxton Schultz (Relief Pitcher) — Elbow (Right): The Nationals placed Schultz on the 15-day injured list Monday, retroactive to Sunday, due to right elbow inflammation. (Mar 23 — 4d ago) [KNOWN] Josiah Gray (Starting Pitcher) — Elbow (Right): The Nationals optioned Gray to Triple-A Rochester on Thursday. (Mar 23 — 4d ago) [KNOWN] Joan Adon (Relief Pitcher) — Undisclosed (Not Specified): no (Dec 9 — 109d ago) [KNOWN] Derek Law (Relief Pitcher) — Forearm (Right): Law (forearm) signed a minor-league contract with the Diamondbacks on Tuesday, Aaron Hughes of SI.com reports. (Jan 27 — 59d ago)

About this analysis

Who made it
Gary AI, an AI sports-analysis product operated by Gary A.I. LLC. No human reviewer is claimed unless one is explicitly named.
Published data
Board stored March 28, 2026 at 12:34 PM ET.
Odds record
The displayed line is the value retained with the call. Stored sportsbook sources: fanduel, fanatics, caesars, betmgm, draftkings, betrivers.
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